The information basis for medical follow-up of exposed population and analysis of medical consequences of radiation exposure is the medical and dosimetric database "Man". The registry of the exposed population began to be formed in the URCRM in 1967 and contains personalized information about both the exposed people themselves and their offspring.

Several cohorts have been created to perform epidemiological analysis (the South Urals Population of Exposed Radiation (SUPER) cohort, the cohort of Antenatally Exposed Population, and the cohort of First-Generation Offspring of exposed parents). The vital status of the cohort members is updated annually. Medical certificates of death are the sources of information about cause of death. The catchment area where the information is updated includes the administrative territory of the Chelyabinsk and Kurgan Oblasts.