Her earliest work on the effects of treatment for tinea capitis in Israel is considered a groundbreaking classic. She led research clarifying the risks related to external radiation among atomic bomb survivors and, most recently, was conducting a study of persons who received CT scans before the age of 18 years. She investigated the effects of internal radiation through several cohorts of patients exposed to diagnostic or therapeutic I-131 and among persons exposed to radionuclides from the Chernobyl accident and the Mayak nuclear facility in Ozyorsk, Russia. She had a long-standing interest in the etiology of thyroid tumors, and led an international effort that pooled 13 studies and contributed greatly to our understanding of the disease.